Solar energy paper index
Environmental and cell-cell signaling shape developmental trajectories across morphogenetic landscapes
One-line summary
A solar energy research paper on Environmental and cell-cell signaling shape developmental trajectories across morphogenetic landscapes.
Engineering notes
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Chinese explanation / 中文解读
中文解读待补充：本站会优先为光伏效率、钙钛矿太阳能电池、储能技术、太阳能热利用、BIPV、并网技术等高价值论文补充中文说明。
Original abstract
Despite the variability in gene regulation and environmental conditions, development of an organism occurs through a sequence of highly coordinated patterning processes. Cells integrate different signals to accurately infer their position in order to adopt an appropriate identity. Using a model of epigenetic landscape originally proposed by Waddington to describe cell-fate determination, we establish the critical role played by juxtacrine signaling between cells in determining tissue patterns. Subsequently we systematically coarse-grain the model at the tissue scale to map its patterning to transition between states in a binary spin model having a free energy landscape. We show that such landscapes serve as a powerful unifying framework for describing development of biological systems across distinct spatio-temporal scales.
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